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Enzyme

local MCP server

Enzyme is a local MCP server: Semantic search and pattern discovery for Obsidian and markdown vaults. Install it from mcpb as https://github.com/byenzyme/enzyme/releases/download/v0.10.2/enzyme-mcp-0.10.2-macos-arm64.mcpb.

What you need

  • Runtime: Claude Desktop (one-click .mcpb bundle) or Claude Desktop (one-click .mcpb bundle) or Claude Desktop (one-click .mcpb bundle) or Claude Desktop (one-click .mcpb bundle).
  • MCP client: Claude Code, Codex, Antigravity, Claude Desktop, Cursor or any other client that speaks MCP over stdio.
  • Environment variables: ENZYME_VAULT_PATH

Summary

Semantic search and pattern discovery for Obsidian and markdown vaults.

Enzyme vs similar servers

ServerStarsTypeAPI keyRuntime
Enzyme85LocalYesmcpb
Obsidian Hybrid Search106LocalYesnpm
Obsidian Everywhere15LocalNonpm
arxiv-mcp-server3,177LocalYespypi
SoloMD1,130LocalNomcpb

Questions

It reads one environment variable: ENZYME_VAULT_PATH. Set them in your MCP config before starting the server.

Claude Desktop (one-click .mcpb bundle) or Claude Desktop (one-click .mcpb bundle) or Claude Desktop (one-click .mcpb bundle) or Claude Desktop (one-click .mcpb bundle), plus an MCP client such as Claude Code, Codex, Claude Desktop or Cursor.

Enzyme is a local MCP server distributed as the mcpb package https://github.com/byenzyme/enzyme/releases/download/v0.10.2/enzyme-mcp-0.10.2-macos-arm64.mcpb.

Similar MCP servers

NameStars
  1. Obsidian Hybrid Searchio.github.flowing-abyss/obsidian-hybrid-search106
  2. Obsidian Everywhereio.github.junnnnnw00/obsidian-everywhere15
  3. arxiv-mcp-serverio.github.blazickjp/arxiv-mcp-server3,177
  4. SoloMDio.github.zhitongblog/solomd1,130
  5. one-search-mcpio.github.yokingma/one-search-mcp143
  6. Vault Cortexio.github.aliasunder/vault-cortex21
  7. Obsidian Brainio.github.sweir1/obsidian-brain11
  8. Firecrawl MCP Serverio.github.firecrawl/firecrawl-mcp-server7,526